
Principal Investigator
Kristopher T. Kahle, M.D., Ph.D.
Pediatric Neurosurgeon | Neurosurgeon | Geneticist
- Director, Pediatric Neurosurgery, Massachusetts General Hospital
- Director, Harvard Center for Hydrocephalus and Neurodevelopmental Disorders (HAND)
- Member, Yale-NIH Centers for Mendelian Genomics
Dr. Kahle is the Director of Pediatric Neurosurgery at the Massachusetts General Hospital (MGH) and the Harvard Center for Hydrocephalus and Neurodevelopmental Disorders (HAND). He is a board-certified pediatric neurosurgeon, with experience in a broad range of pediatric neurosurgical disorders including brain and spinal cord tumors and cysts, all types of hydrocephalus, Chiari malformation, spina bifida, vascular malformations, and others. He also treats these conditions in transitional age patients and adults, providing continuity of care across the age spectrum. He is highly skilled in both open and endoscopic/minimally invasive neurosurgical techniques.
Dr. Kahle is a fellow of the American Association of Neurological Surgeons (AANS) and a member of numerous medical organizations, including the AANS, Congress of Neurological Surgeons (CNS), American Society of Pediatric Neurosurgeons (ASPN), and the International Society of Pediatric Neurosurgeons (ISPN).
Dr. Kahle graduated cum laude from the University of Chicago in 1999 with degrees in Biology and Philosophy. He received his M.D. from Yale School of Medicine in 2007, where he also received his Ph.D. working in the laboratory of human geneticist Richard Lifton. He completed his neurosurgery residency training at MGH in 2014, as well as a post-doctoral research fellowship at Harvard University with co-mentors Stephen Elledge and David Clapham. He completed a clinical pediatric neurosurgery fellowship at Boston Children’s Hospital, where he was Shellito staff associate and Instructor of Neurosurgery at Harvard Medical School. Dr. Kahle returned to New Haven to join the Yale School of Medicine faculty, where he was Assistant Professor of Neurosurgery, Pediatrics, and Cellular & Molecular Physiology, and Director of Neonatal and Congenital Anomaly Neurosurgery from 2016-2021. In 2021, Dr. Kahle came to Massachusetts General Hospital to serve as Director of Pediatric Neurosurgery. He is also Nicholas T. Zervas Associate Professor of Neurosurgery at Harvard Medical School, Associate Member of Broad Institute of MIT and Harvard, and Investigator for the Division of Genetics and Genomics at Boston Children's Hospital.

Garrett Allington, PhD
MD Candidate
Columbia University

Julie Choi
PhD Candidate
Washington University School of Medicine

Evan Dennis
MD Candidate
Harvard Medical School

Tyrone Despenza Jr.
MD/PhD Candidate
Yale School of Medicine

Baojian Fan, MD, PhD
Research Scientist
Massachusetts General Hospital

Carla Fortes
Clinical Research Program/
Project Manager
Massachusetts General Hospital

Po-Ying Fu
Bioinformatics Research Analyst
Washington University in St. Louis

Kristin Hanifin, MSN, APRN, CPNP
Nurse Practitioner
Massachusetts General Hospital

Sheng Chih (Peter) Jin, PhD
Assistant Professor, Researcher
Washington University in St. Louis

Emre Kiziltug
MD Candidate
Yale School of Medicine

Adam Kundishora, MD
Fellow in Pediatric Neurosurgery
Children's Hospital of Philadelphia

Arnaud Marlier, PhD
Senior Research Scientist

Neel Mehta
MD Candidate
Harvard Medical School

Quentin Moyer
MD Candidate
Harvard Medical School

Kedous Yared Mekbib, MD, MHS
Neurosurgery Resident
Mayo Clinic

Susan P. Mullany, NP
Nurse Practitioner
Massachusetts General Hospital

Andres Moreno De Luca, MD
Associate Neuroradiologist
Assistant Professor
Geisinger

William Muñoz Miranda, MD, PhD
Neurosurgery Resident
Massachusetts General Hospital

Carol Nelson-Williams
Senior Research Scientist
Yale University

Jack Ocken
Undergraduate Research Associate
Yale College

Paulina Piwowarczyk
Research Associate
Boston Children's Hospital

Benjamin Reeves
MD/PhD Candidate
Yale School of Medicine

JP Shohfi
Administrator
Clinical Research Coordinator
Massachusetts General Hospital

Stephanie Robert, MD, PhD
Resident Physician, Department of Neurosurgery
Postdoctoral Fellow, Kahle Lab
Yale New Haven Hospital

Hannah Smith, BS
Research/ Grant Consultant
Massachusetts General Hospital

Myron Rolle, MD, MSc
Neurosurgery Resident
Massachusetts General Hospital

Yung-Chun (David) Wang, PhD
Postdoctoral Research Associate
Washington University in St. Louis

Max Wrubel
Research Associate
McDonnell Genome Institute

Shujuan Zhao
PhD Candidate
Washington University in St. Louis
Lab Alumni

August Allocco
MD Candidate
Yale School of Medicine

Weilai Dong
PhD Candidate
Yale University

Sierra Conine
Postgraduate Associate in Neurosurgery
Yale University

Ashley Dunbar, MD
Neurosurgery Resident
Washington University School of Medicine

Eyiyemisi Damisah, MD
Assistant Professor of Neurosurgery
Yale University

Daniel Duran, MD
Neurosurgery Resident
University of Mississippi Medical Center

Charuta Furey, MD
Neurosurgery Resident
Barrow Neurological Institute

Jonathan Gaillard, MD, MS
Child Neurology Resident
University of Michigan

Ava Hunt, MD
Pediatric Resident
Children's Hospital of Philadelphia

Jason Karimy, MD
Rural Family Medicine Resident
Appalachian Regional Healthcare

Shreyas Panchagnula, MD, MHS
Neurosurgery Resident
University of Maryland

Duy Phan, MD, PhD
Neurosurgery Resident
University of Virginia

Amar Sheth
MD Candidate
Yale School of Medicine
.jpg)
Amrita Singh, MD
Neurosurgery Resident
Columbia University

Will Sullivan
Yale College

Xue Zeng
Computational Biologist
Senior Scientist, Amgen
